{"id":4874,"date":"2026-08-13T13:41:39","date_gmt":"2026-08-13T05:41:39","guid":{"rendered":"https:\/\/www.pgeneral.com\/?p=4874"},"modified":"2026-08-13T13:41:39","modified_gmt":"2026-08-13T05:41:39","slug":"pharmacopoeia-of-the-peoples-republic-of-china-2025-edition-protocol-determination-of-curdione-and-germacrone-in-wenyujin-rhizoma-preparatum","status":"publish","type":"post","link":"https:\/\/www.pgeneral.com\/pt\/applications\/pharmacopoeia-of-the-peoples-republic-of-china-2025-edition-protocol-determination-of-curdione-and-germacrone-in-wenyujin-rhizoma-preparatum","title":{"rendered":"Protocolo da Farmacopeia da Rep\u00fablica Popular da China (Edi\u00e7\u00e3o de 2025) \u2013 Determina\u00e7\u00e3o de curdiona e germacrona na prepara\u00e7\u00e3o do rizoma de Wenyujin"},"content":{"rendered":"<p>A determina\u00e7\u00e3o de curdiona e germacrona em Wenyujin Rhizoma Preparatum foi recentemente inclu\u00edda no <em>Farmacopeia da Rep\u00fablica Popular da China (Edi\u00e7\u00e3o de 2025)<\/em>De acordo com as condi\u00e7\u00f5es cromatogr\u00e1ficas especificadas na edi\u00e7\u00e3o de 2025 da Farmacopeia Chinesa, foi estabelecido um m\u00e9todo para a an\u00e1lise quantitativa de curdiona e germacrona em Wenyujin Rhizoma Preparatum utilizando uma coluna cromatogr\u00e1fica C18.<\/p>\n<p>Os resultados demonstram que, nos testes de repetibilidade da solu\u00e7\u00e3o padr\u00e3o de refer\u00eancia, os seguintes valores de RSD (desvio padr\u00e3o relativo) do tempo de reten\u00e7\u00e3o para curdiona e germacrona foram \u2264 0,091%; o RSD da \u00e1rea do pico foi \u2264 0,328%; os fatores de cauda foram 1,035 e 1,019, respectivamente; o n\u00famero de pratos te\u00f3ricos do pico de germacrona atingiu 152.410, atendendo aos requisitos da norma. <em>Farmacopeia da Rep\u00fablica Popular da China (Edi\u00e7\u00e3o de 2025)<\/em>Este m\u00e9todo pode servir como refer\u00eancia para a determina\u00e7\u00e3o de curdiona e germacrona em Wenyujin Rhizoma Preparatum.<\/p>\n<h2><strong><b>I. Condi\u00e7\u00f5es do instrumento<\/b><\/strong><\/h2>\n<ul>\n<li>Cromat\u00f3grafo L\u00edquido de Alta Efici\u00eancia Persee L820<\/li>\n<li>Bomba bin\u00e1ria de gradiente de alta press\u00e3o L820-P22<\/li>\n<li>Amostrador autom\u00e1tico L820-A11<\/li>\n<li>Forno de coluna L820-C11<\/li>\n<li>Detector UV-Vis L820-D10<\/li>\n<li>Esta\u00e7\u00e3o de trabalho padr\u00e3o para cromatografia LCWin V5.0<\/li>\n<li>Bandeja de solvente L820-C304100001<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>The determination of curdione and germacrone in Wenyujin Rhizoma Preparatum is newly included in the Pharmacopoeia of the People\u2019s Republic of China (2025 Edition). In accordance with the chromatographic conditions specified in the 2025 Edition Chinese Pharmacopoeia, a method was established for the quantitative analysis of curdione and germacrone in Wenyujin Rhizoma Preparatum using a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4664,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[36,73],"tags":[],"class_list":["post-4874","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-applications","category-food-and-drugs"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/posts\/4874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/comments?post=4874"}],"version-history":[{"count":1,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/posts\/4874\/revisions"}],"predecessor-version":[{"id":4875,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/posts\/4874\/revisions\/4875"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/media\/4664"}],"wp:attachment":[{"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/media?parent=4874"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/categories?post=4874"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pgeneral.com\/pt\/wp-json\/wp\/v2\/tags?post=4874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}