{"id":4265,"date":"2026-01-12T00:00:18","date_gmt":"2026-01-11T16:00:18","guid":{"rendered":"https:\/\/www.pgeneral.com\/?p=4265"},"modified":"2026-01-14T10:24:16","modified_gmt":"2026-01-14T02:24:16","slug":"high-resolution-mass-spectrometry-defining-resolution-in-analytical-terms","status":"publish","type":"post","link":"https:\/\/www.pgeneral.com\/ja\/news\/high-resolution-mass-spectrometry-defining-resolution-in-analytical-terms\/","title":{"rendered":"\u89e3\u50cf\u5ea6\u3092\u5b9a\u7fa9\u3059\u308b\u9ad8\u89e3\u50cf\u5ea6\u8cea\u91cf\u5206\u5149\u8a08"},"content":{"rendered":"<p>&nbsp;<\/p>\n<div style=\"text-align: center;\"><img decoding=\"async\" src=\"https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/High-Resolution-Mass-Spectrometry-Defining-Resolution-in-Analytical-Terms.webp\" alt=\"\u89e3\u50cf\u5ea6\u3092\u5b9a\u7fa9\u3059\u308b\u9ad8\u89e3\u50cf\u5ea6\u8cea\u91cf\u5206\u5149\u8a08\" \/><\/div>\n<p>\u9ad8\u89e3\u50cf\u5ea6\u8cea\u91cf\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u30fc\uff08HRMS\uff09\u3067\u306f\u3001\u89e3\u50cf\u5ea6\u306f\u30c7\u30d0\u30a4\u30b9&#8217;\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u307b\u307c\u540c\u3058\u8cea\u91cf\u304b\u3089\u5145\u96fb\uff08m\/z\uff09\u5024\u3092\u6301\u3064\u30a4\u30aa\u30f3\u3092\u533a\u5225\u3059\u308b\u80fd\u529b\u3002\u3053\u306e\u30b9\u30ad\u30eb\u306f\u3001\u7279\u306b\u96e3\u3057\u3044\u6df7\u5408\u7269\u3067\u5316\u5408\u7269\u3092\u6b63\u3057\u304f\u898b\u3064\u3051\u308b\u305f\u3081\u306b\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002\u6570\u5b66\u7684\u306b\u8a00\u3048\u3070\u3001\u89e3\u50cf\u5ea6\u306fR = m\/\u0394m\u3068\u8868\u3055\u308c\u307e\u3059\u3002\u3053\u3053\u3067\u3001&#8220;m&#8221;\u30e1\u30a4\u30f3\u30d4\u30fc\u30af\u306em\/z\u3092\u8868\u3057\u3001&#8220;\u0394m&#8221;\u30d4\u30fc\u30af&#8217;\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u6700\u5927\u534a\u5e45\u3067\u5168\u5e45\uff08FWHM\uff09\u3067s\u306e\u5e45\u3002\u3053\u306e\u5b9a\u7fa9\u65b9\u6cd5\u306f,\u7570\u306a\u308b\u30c7\u30d0\u30a4\u30b9\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u78ba\u8a8d\u3059\u308b\u6a19\u6e96\u7684\u306a\u65b9\u6cd5\u3092\u63d0\u4f9b\u3057\u307e\u3059.<\/p>\n<p>\u89e3\u50cf\u5ea6\u306f\u30012\u3064\u306e\u30d4\u30fc\u30af\u304c\u57fa\u76e4\u306e\u5e73\u5747\u5e45\uff08tR2 &gt; tR1\uff09\u306b\u57fa\u3065\u3044\u3066\u3069\u306e\u3088\u3046\u306b\u5206\u96e2\u3059\u308b\u304b\u3092\u898b\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8a08\u7b97\u3057\u307e\u3059\u3002\u5f37\u3044\u89e3\u50cf\u5ea6\u306f,\u6b63\u78ba\u306a\u8cea\u91cf\u30c1\u30a7\u30c3\u30af\u3092\u53ef\u80fd\u306b\u3057,\u975e\u5e38\u306b\u8fd1\u3044\u540d\u76ee\u8cea\u91cf\u306e\u5316\u5408\u7269\u3092\u5206\u985e\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059.\u3088\u3044\u89e3\u50cf\u5ea6\u304c\u306a\u3051\u308c\u3070\u3001\u7c21\u5358\u306b\u6df7\u305c\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<h3 id=\"what-are-the-different-metrics-used-to-quantify-resolution-in-hrms\"><strong>HRMS\u3067\u89e3\u50cf\u5ea6\u3092\u91cf\u5316\u3059\u308b\u305f\u3081\u306b\u4f7f\u7528\u3055\u308c\u308b\u7570\u306a\u308b\u30e1\u30c8\u30ea\u30c3\u30af\u30b9\u306f\u4f55\u3067\u3059\u304b\uff1f<\/strong><\/h3>\n<p>\u5c02\u9580\u5bb6\u306f\u3044\u304f\u3064\u304b\u306e\u65b9\u6cd5\u3067\u89e3\u50cf\u5ea6\u3092\u6e2c\u5b9a\u3057\u307e\u3059\u3002FWHM\u65b9\u6cd5\u306f\u307b\u3068\u3093\u3069\u306e\u4eba\u304c\u4f7f\u3046\u65b9\u6cd5\u3067\u3059\u3002\u30c7\u30d0\u30a4\u30b9\u304c\u3069\u306e\u3088\u3046\u306b\u6a5f\u80fd\u3057\u3066\u3044\u308b\u304b\u3092\u30c1\u30a7\u30c3\u30af\u3059\u308b\u3068\u304d\u306b\u72b6\u6cc1\u3092\u5b89\u5b9a\u3055\u305b\u307e\u3059\u3002\u5225\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u300110\uff05\u306e\u8c37\u6cd5\u306f\u3001\u5f37\u5ea6\u304c\u4f4e\u3044\u5834\u6240\u3067\u30d4\u30fc\u30af\u306e\u5206\u96e2\u3092\u30c1\u30a7\u30c3\u30af\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u306f\u4e8b\u5b9f\u5f8c\u306b\u89e3\u50cf\u5ea6\u756a\u53f7\u3092\u5909\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30d4\u30fc\u30af\u30af\u30ea\u30fc\u30f3\u30a2\u30c3\u30d7\u3068\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3092\u56fa\u5b9a\u3059\u308b\u30c4\u30fc\u30eb\u306f,\u3053\u308c\u3089\u306e\u6570\u5b57\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b.\u3053\u308c\u306f\u3001\u91cd\u53e0\u3059\u308b\u30d4\u30fc\u30af\u3084\u30d4\u30d4\u30fc\u30af\u304c\u30d4\u30d4\u30fc\u30af\u306b\u91cd\u53e0\u3059\u308b\u5834\u5408\u3084\u3001\u4fe1\u4fe1\u4fe1\u53f7\u304c\u30d4\u30d4\u30fc\u30af\u306b\u6bd4\u3079\u3066\u5f31\u3044\u3068\u304d\u306b\u983b\u7e41\u306b\u8d77\u3053\u308a\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u6700\u7d42\u30ec\u30dd\u30fc\u30c8\u306f\u51e6\u7406\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h2 id=\"factors-influencing-mass-spectrometric-resolution\"><strong>\u8cea\u91cf\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u30c3\u30af\u89e3\u50cf\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8981\u56e0<\/strong><\/h2>\n<p>\u8cea\u91cf\u5206\u6790\u5668\u306e\u69cb\u7bc9\u65b9\u6cd5\u306f\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002JEOL\u306e\u30e6\u30cb\u30c3\u30c8\u306a\u3069\u306e\u307b\u3068\u3093\u3069\u306eTOFMS\u30e6\u30cb\u30c3\u30c8\u306f,\u5805\u5b9f\u306a\u8cea\u91cf\u306e\u8a73\u7d30\u3068\u6b63\u78ba\u306a\u8cea\u91cf\u306e\u8aad\u307f\u53d6\u308a\u3092\u63d0\u4f9b\u3057\u307e\u3059.\u305d\u306e\u305f\u3081\u3001\u5f7c\u3089\u306f\u614e\u91cd\u306a\u91cf\u30c1\u30a7\u30c3\u30af\u3092\u901a\u3058\u3066\u57fa\u672c\u7684\u306a\u30e1\u30a4\u30af\u30a2\u30c3\u30d7\u3092\u898b\u3064\u3051\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30a4\u30aa\u30f3\u306e\u7d4c\u8def\u3068\u30a4\u30aa\u30f3\u306e\u79fb\u52d5\u65b9\u6cd5\u306f\u3001\u691c\u51fa\u5668\u306b\u6253\u3064\u524d\u306b\u7126\u70b9\u3092\u5f62\u6210\u3057\u307e\u3059\u3002\u4fe1\u53f7\u3092\u691c\u51fa\u3057 \u5f37\u5316\u3059\u308b\u90e8\u54c1\u3082\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059 \u653e\u5927\u306e\u305f\u3081\u306e\u96fb\u5b50\u6a5f\u5668\u3084 \u30b5\u30f3\u30d7\u30ea\u30f3\u30b0\u306e\u983b\u5ea6\u306a\u3069\u3067\u3059\u30a4\u30aa\u30f3\u60c5\u5831\u3092\u660e\u78ba\u306b\u4fdd\u3061\u3001\u3088\u308a\u3088\u3044\u5168\u4f53\u7684\u306a\u89e3\u50cf\u5ea6\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/p>\n<h3 id=\"how-do-operational-conditions-modify-instrument-resolution\"><strong>\u64cd\u4f5c\u6761\u4ef6\u306f\u3069\u306e\u3088\u3046\u306b\u5100\u5668\u306e\u89e3\u50cf\u5ea6\u3092\u5909\u3048\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/strong><\/h3>\n<p>\u71b1,\u96fb\u5b50\u5f37\u5ea6,\u7a7a\u6c17\u5727\u3092\u542b\u3080\u30a4\u30aa\u30f3\u6e90\u306e\u8a2d\u5b9a\u306f,\u30a4\u30aa\u30f3\u306e\u5f62\u6210\u3068\u62e1\u6563\u306e\u7a0b\u5ea6\u3092\u5909\u3048\u308b.\u6e29\u5ea6\u304c\u9ad8\u304f,\u96fb\u5727\u304c\u8abf\u6574\u3055\u308c,\u30a4\u30aa\u30f3\u5316\u304c\u3088\u308a\u5747\u5300\u306b\u306a\u308a\u307e\u3059.\u3057\u304b\u3057\u3001\u5206\u5b50\u306e\u4e0d\u8981\u306a\u65ad\u88c2\u3084\u5f31\u3044\u4fe1\u53f7\u3092\u9632\u3050\u305f\u3081\u306b\u3001\u305d\u308c\u3089\u3092\u6ce8\u610f\u3057\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u3082\u3046\u4e00\u3064\u306e\u91cd\u8981\u306a\u30dd\u30a4\u30f3\u30c8\u306f\u3001\u30c7\u30d0\u30a4\u30b9\u306e\u30b9\u30ad\u30e3\u30f3\u901f\u5ea6\u3067\u3059\u3002\u8fc5\u901f\u306a\u30b9\u30ad\u30e3\u30f3\u306b\u3088\u308a,\u4fe1\u53f7\u306e\u8a73\u7d30\u3092\u53d6\u5f97\u3059\u308b\u6642\u9593\u304c\u77ed\u7e2e\u3055\u308c,\u89e3\u50cf\u5ea6\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059.\u540c\u6642\u306b\u3001\u30b5\u30f3\u30d7\u30eb\u5185\u306e\u7269\u8cea\u3001\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u3088\u3046\u306b\u3001\u30a4\u30aa\u30f3\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u3088\u308a\u5e83\u3044\u307e\u305f\u306f\u66f2\u304c\u3063\u305f\u30d4\u30fc\u30af\u306b\u3064\u306a\u304c\u308a\u3001\u30c7\u30d0\u30a4\u30b9\u3092\u5207\u65ad\u3057\u307e\u3059&#8217;\u5206\u96e2\u3059\u308b\u529b\u3002\u3057\u305f\u304c\u3063\u3066,\u614e\u91cd\u306a\u8abf\u6574\u306f,\u5f37\u3044\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u7dad\u6301\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059.<\/p>\n<h2 id=\"comparison-between-high-resolution-and-low-resolution-mass-spectrometry\"><strong>\u9ad8\u89e3\u50cf\u5ea6\u3068\u4f4e\u89e3\u50cf\u5ea6\u8cea\u91cf\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u306e\u6bd4\u8f03<\/strong><\/h2>\n<p>\u9ad8\u89e3\u50cf\u5ea6\u306e\u30c7\u30d0\u30a4\u30b9\u306f,\u30bf\u30fc\u30b2\u30c3\u30c8\u3092\u9078\u629e\u3057,\u7d50\u679c\u3078\u306e\u4fe1\u983c\u3092\u7bc9\u304f\u306e\u306b\u5927\u304d\u306a\u5229\u70b9\u3092\u3082\u305f\u3089\u3057\u307e\u3059.\u5f7c\u3089\u306f\u540c\u3058\u57fa\u672c\u8cea\u91cf\u6570\u3092\u5171\u6709\u3059\u308b\u30a4\u30aa\u30f3\u3067\u3055\u3048\u8cea\u91cf\u3092\u5206\u5272\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u5143\u7d20\u306e\u69cb\u6210\u3092\u4f5c\u308a\u51fa\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u4f3c\u305f\u3082\u306e\u306b\u6e80\u3061\u305f\u30b5\u30f3\u30d7\u30eb\u3084\u5316\u5408\u7269\u306e\u30bb\u30c3\u30c8\u30ea\u30b9\u30c8\u306a\u3057\u3067\u691c\u7d22\u3059\u308b\u3068\u304d\u306b\u975e\u5e38\u306b\u6709\u7528\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u3089\u306e\u30b7\u30b9\u30c6\u30e0\u306f\u3001\u3088\u308a\u826f\u3044\u8cea\u91cf\u7cbe\u5ea6\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u5206\u5b50\u5f0f\u3068\u30ea\u30f3\u30af\u3059\u308b\u78ba\u5b9f\u6027\u3092\u9ad8\u3081\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u6a5f\u80fd\u306f\u3001\u74b0\u5883\u76e3\u8996\u3084\u85ac\u54c1\u306e\u54c1\u8cea\u306e\u30c1\u30a7\u30c3\u30af\u306a\u3069\u306e\u5206\u91ce\u3067\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u8981\u3059\u308b\u306b\u3001\u9ad8\u89e3\u50cf\u5ea6\u306f\u96e3\u3057\u3044\u5206\u6790\u306e\u305f\u3081\u306e\u30b2\u30fc\u30e0\u3092\u4e0a\u3052\u307e\u3059\u3002<\/p>\n<h3 id=\"what-are-the-limitations-of-using-high-resolution-ms\"><strong>\u9ad8\u89e3\u50cf\u5ea6MS\u306e\u4f7f\u7528\u306e\u5236\u9650\u306f\u4f55\u3067\u3059\u304b\uff1f<\/strong><\/h3>\n<p>\u5f37\u307f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u9ad8\u89e3\u50cf\u5ea6\u30bb\u30c3\u30c8\u30a2\u30c3\u30d7\u306f\u57fa\u672c\u7684\u306a\u30bb\u30c3\u30c8\u30a2\u30c3\u30d7\u3088\u308a\u3082\u30b3\u30b9\u30c8\u304c\u9ad8\u304f\u3001\u5b9f\u884c\u3059\u308b\u306b\u306f\u3088\u308a\u591a\u304f\u306e\u52aa\u529b\u304c\u5fc5\u8981\u3067\u3059\u3002\u6a5f\u80fd\u3092\u826f\u304f\u7d9a\u3051\u308b\u305f\u3081\u306b\u7279\u5225\u306a\u8abf\u6574\u624b\u9806\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u30c7\u30fc\u30bf\u3092\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u30b9\u30de\u30fc\u30c8\u306a\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u306b\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002Orbitraps\u3084FT-ICR\u306e\u3088\u3046\u306a\u30e6\u30cb\u30c3\u30c8\u306f,\u5468\u56f2\u306e\u53b3\u683c\u306a\u5236\u5fa1\u3068\u5b89\u5b9a\u3057\u305f\u30e1\u30f3\u30c6\u30ca\u30f3\u30b9\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059.What&#8217;\u3055\u3089\u306b\u3001\u3053\u308c\u3089\u306e\u5b9f\u884c\u304b\u3089\u306e\u5927\u91cf\u306e\u30c7\u30fc\u30bf\u306f\u3001\u3059\u3079\u3066\u3092\u51e6\u7406\u3059\u308b\u305f\u3081\u306b\u5f37\u529b\u306a\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u5f37\u529b\u306a\u3082\u306e\u306e\u3001\u5168\u4f53\u7684\u306b\u306f\u3088\u308a\u591a\u304f\u306e\u8cc7\u6e90\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002<\/p>\n<h2 id=\"applications-requiring-high-resolution-mass-spectrometry\"><strong>\u9ad8\u89e3\u50cf\u5ea6\u8cea\u91cf\u5206\u5149\u8a08\u3092\u5fc5\u8981\u3068\u3059\u308b\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3<\/strong><\/h2>\n<p>&nbsp;<\/p>\n<div style=\"text-align: center;\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-4264\" src=\"https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/gas-chromatography-G5-GC.webp\" alt=\"\u30ac\u30b9\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30d5\u30a3\u30fc G5 GC\" width=\"1020\" height=\"586\" srcset=\"https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/gas-chromatography-G5-GC.webp 1020w, https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/gas-chromatography-G5-GC-300x172.webp 300w, https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/gas-chromatography-G5-GC-768x441.webp 768w, https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/gas-chromatography-G5-GC-18x10.webp 18w, https:\/\/www.pgeneral.com\/wp-content\/uploads\/2026\/01\/gas-chromatography-G5-GC-600x345.webp 600w\" sizes=\"(max-width: 1020px) 100vw, 1020px\" \/><\/div>\n<p>\u591a\u304f\u306e\u5316\u5408\u7269\u304c\u6df7\u5408\u3055\u308c\u305f\u74b0\u5883\u3084\u751f\u547d\u30b5\u30f3\u30d7\u30eb\u306e\u3088\u3046\u306a\u53b3\u3057\u3044\u74b0\u5883\u3067\u306f,HRMS\u306f,\u30ea\u30b9\u30c8\u306b\u30de\u30c3\u30c1\u3059\u308b\u3060\u3051\u3067\u672a\u77e5\u306e\u3082\u306e\u3092\u898b\u3064\u3051\u308b\u3053\u3068\u3067\u7279\u5fb4\u4ed8\u3051\u3066\u3044\u307e\u3059.\u8a73\u7d30\u306aTOFMS\u306f,\u56f3\u66f8\u9928\u306e\u52a9\u3051\u306a\u3057\u3067,\u672a\u77e5\u306e\u9805\u76ee\u3092\u72ec\u81ea\u3067\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059.\u5e45\u5e83\u3044\u691c\u7d22\u306b\u9069\u3057\u3066\u3044\u307e\u3059\u3002\u6b63\u78ba\u306a\u8cea\u91cf\u306e\u90e8\u5206\u3068\u540c\u4f4d\u7d20\u306e\u5146\u5019\u306f,\u69cb\u9020\u3092\u898b\u3064\u3051\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059.\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u8907\u96d1\u3055\u3092\u76f4\u63a5\u53d6\u308a\u6271\u3046\u304b\u3089\u660e\u308b\u3044\u3002\u305f\u3068\u3048\u3070\u3001\u6df7\u96d1\u3057\u305f\u30b5\u30f3\u30d7\u30eb\u3067\u306f\u3001\u3088\u308a\u30b7\u30f3\u30d7\u30eb\u306a\u30c4\u30fc\u30eb\u304c\u6b20\u3051\u3066\u3044\u308b\u8a73\u7d30\u3092\u5f15\u304d\u51fa\u3057\u307e\u3059\u3002 \u3057\u305f\u304c\u3063\u3066\u3001\u4f55\u306b\u3064\u3044\u3066\u3088\u308a\u6df1\u3044\u6d1e\u5bdf\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059&#8217;S \u73fe\u5728\u3002<\/p>\n<h3 id=\"how-does-hrms-enhance-quantitative-workflows\"><strong>HRMS\u306f\u3069\u306e\u3088\u3046\u306b\u91cf\u7684\u30ef\u30fc\u30af\u30d5\u30ed\u30fc\u3092\u5f37\u5316\u3057\u307e\u3059\u304b\uff1f<\/strong><\/h3>\n<p>\u4ee3\u8b1d\u7269\u7406\u5b66\u3084\u30d7\u30ed\u30c6\u30aa\u30df\u30af\u30b9\u306a\u3069\u306e\u5206\u91ce\u3067\u306e\u30bf\u30b9\u30af\u3092\u30ab\u30a6\u30f3\u30c8\u3059\u308b\u306b\u306f,HRMS\u306f\u305d\u306e\u30c8\u30c3\u30d7\u30ce\u30c3\u30c1\u306e\u30d4\u30c3\u30ad\u30f3\u30b0\u30d1\u30ef\u30fc\u3067\u5f79\u7acb\u3061\u307e\u3059.\u3053\u308c\u306b\u3088\u308a\u3001\u540c\u69d8\u306e\u69cb\u9020\u3084\u80cc\u666f\u306e\u6df7\u4e71\u306e\u4e2d\u3067\u52b4\u50cd\u8005\u304c\u76ee\u6a19\u3092\u6c7a\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002SRM\u306f,\u6a19\u7684m\/z\u304c\u5e72\u6e09\u7269\u3068\u4e00\u81f4\u3059\u308b\u30a8\u30ad\u30b9\u30c8\u30e9\u3067\u8377\u8f09\u3055\u308c\u305f\u30b5\u30f3\u30d7\u30eb\u3067\u3082,\u654f\u611f\u3067\u5b89\u5b9a\u3057\u305f\u30ab\u30a6\u30f3\u30c8\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059.\u305d\u306e\u305f\u3081,HRMS\u306f,\u4e0d\u8981\u306a\u7269\u8cea\u3084\u6b8b\u7559\u7269\u306e\u5fae\u5c0f\u306a\u75d5\u8de1\u3092\u691c\u67fb\u3059\u308b\u305f\u3081\u306b\u826f\u304f\u6a5f\u80fd\u3057\u307e\u3059.\u898f\u5236\u3055\u308c\u305f\u4f5c\u696d\u3067\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u6570\u5b57\u3092\u78ba\u4fdd\u3057\u307e\u3059\u3002<\/p>\n<h2 id=\"techniques-to-optimize-or-improve-ms-resolution-performance\"><strong>MS\u89e3\u50cf\u5ea6\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u6700\u9069\u5316\u307e\u305f\u306f\u6539\u5584\u3059\u308b\u305f\u3081\u306e\u6280\u8853<\/strong><\/h2>\n<p>\u30a4\u30aa\u30f3\u30d1\u30b9\u3092\u8abf\u6574\u3057,\u30a4\u30aa\u30f3\u3092\u6307\u5c0e\u3059\u308b\u30ec\u30f3\u30ba\u306e\u96fb\u5727\u3092\u6b63\u78ba\u306b\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067,\u6563\u6563\u3092\u6e1b\u3089\u3057,\u7126\u70b9\u3092\u5f37\u5316\u3057\u307e\u3059.\u307e\u305f,TOF-MS\u306e\u9577\u3044\u30d1\u30b9\u3084FT-ICR\u306e\u5f37\u3044\u30d5\u30a3\u30fc\u30eb\u30c9\u306a\u3069\u306e\u5206\u6790\u5668\u306e\u8a2d\u5b9a\u306f,\u89e3\u50cf\u5ea6\u3092\u660e\u3089\u304b\u306b\u4e0a\u3052\u307e\u3059.\u30d5\u30ed\u30f3\u30c8\u30d5\u30a3\u30eb\u30bf\u30fc\u306e\u90e8\u54c1\u3092\u5099\u3048\u305f\u56db\u6975\u5206\u6790\u6a5f\u306f,\u6c5a\u308c\u306e\u84c4\u7a4d\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059.\u3053\u308c\u306f\u5b89\u5b9a\u3057\u305f\u8d70\u884c\u3068\u505c\u6b62\u6642\u9593\u3092\u77ed\u7e2e\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u6a5f\u80fd\u306f\u3001\u30c4\u30fc\u30eb\u306e\u3088\u3046\u306a <a href=\"https:\/\/www.pgeneral.com\/ja\/product\/m7\/\"><strong><u>M7\u30b7\u30f3\u30b0\u30eb\u56db\u91cd\u6975GC-MS<\/u><\/strong><\/a>\u3002\u4e3b\u8981\u306a\u90e8\u54c1\u3092\u6e05\u6f54\u306b\u4fdd\u3061\u3001\u65e5\u5e38\u7684\u306a\u6e05\u6f54\u3092\u30b9\u30ad\u30c3\u30d7\u3059\u308b\u5f15\u304d\u51fa\u3057\u524d\u306e\u56db\u6975\u30d5\u30a3\u30eb\u30bf\u30fc\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3 id=\"how-can-software-tools-enhance-resolution-post-acquisition\"><strong>\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u30c4\u30fc\u30eb\u306f\u3069\u306e\u3088\u3046\u306b\u53d6\u5f97\u5f8c\u306e\u89e3\u50cf\u5ea6\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u304b\uff1f<\/strong><\/h3>\n<p>\u6570\u5b66\u30d9\u30fc\u30b9\u306e\u30d4\u30fc\u30af\u30b9\u30d7\u30ea\u30c3\u30bf\u30fc\u306f,\u30c7\u30fc\u30bf\u3067\u671f\u5f85\u3055\u308c\u308b\u5f62\u72b6\u3068\u540c\u4f4d\u7d20\u30b9\u30d7\u30ec\u30c3\u30c9\u3092\u4f7f\u7528\u3057\u3066\u6df7\u5408\u3055\u308c\u305f\u30d4\u30fc\u30af\u3092\u4f5c\u6210\u3057\u307e\u3059.\u30ce\u30a4\u30ba\u3092\u524a\u6e1b\u3059\u308b\u65b9\u6cd5\u3001\u4f8b\u3048\u3070\u30c7\u30b8\u30bf\u30eb\u3067\u6ed1\u3089\u304b\u306b\u3057\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u6f02\u79fb\u3092\u53d6\u308a\u9664\u304f\u306a\u3069\u306f\u3001\u4fe1\u53f7\u3082\u660e\u78ba\u306b\u3057\u307e\u3059\u3002\u9593\u63a5\u7684\u306b\u660e\u78ba\u6027\u3092\u9ad8\u3081 \u89e3\u6c7a\u3092\u52a9\u3051\u307e\u3059\u3057\u3070\u3057\u3070\u3001\u3053\u308c\u3089\u306e\u30c4\u30fc\u30eb\u306f\u3001\u30e9\u30a4\u30d6\u76e3\u7763\u306e\u305f\u3081\u306e\u5b8c\u5168\u306a\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u30b9\u30a4\u30fc\u30c8\u5185\u306b\u7f6e\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<a href=\"https:\/\/www.pgeneral.com\/ja\/product\/%e3%82%b8%e3%83%bc%e3%83%95%e3%82%a1%e3%82%a4%e3%83%96%e3%82%b8%e3%83%bc%e3%82%b7%e3%83%bc\/\"> <strong><u>G5 GC<\/u><\/strong><\/a> \u5236\u5fa1\u306e\u554f\u984c\u306b\u5bfe\u3059\u308b\u30b9\u30de\u30fc\u30c8\u306a\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u304c\u4ed8\u5c5e\u3057\u3066\u3044\u307e\u3059\u3002\u6e29\u5ea6\u8a08\u753b,\u6d41\u308c\u6642\u8a08,\u8907\u6570\u306e\u691c\u51fa\u5668\u306e\u30b5\u30dd\u30fc\u30c8\u3092\u51e6\u7406\u3057\u307e\u3059.\u3053\u306e\u8a2d\u5b9a\u306b\u3088\u308a\u3001\u51e6\u7406\u304c\u3088\u308a\u30b9\u30e0\u30fc\u30ba\u3067\u52b9\u679c\u7684\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<h2 id=\"persee-a-reliable-partner-in-analytical-instrumentation-solutions\"><strong>PERSEE: \u5206\u6790\u5100\u5668\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u306b\u304a\u3051\u308b\u4fe1\u983c\u3067\u304d\u308b\u30d1\u30fc\u30c8\u30ca\u30fc<\/strong><\/h2>\n<p><a style=\"text-decoration: underline;\" href=\"https:\/\/www.pgeneral.com\/ja\/\"><strong>\u5fcd\u8010<\/strong><\/a> 1991\u5e74\u306b\u59cb\u307e\u3063\u305fA <a style=\"text-decoration: underline;\" href=\"https:\/\/www.pgeneral.com\/ja\/%e7%a7%81%e3%81%9f%e3%81%a1%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/\"><strong>\u65b0\u9bae\u306a\u30cf\u30a4\u30c6\u30c3\u30af\u4f01\u696d<\/strong><\/a>\u79d1\u5b66\u30c4\u30fc\u30eb\u306e\u7814\u7a76\u3001\u5efa\u8a2d\u3001\u8ca9\u58f2\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u3044\u307e\u3059\u3002\u5206\u5b50\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u30fc,\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30d5\u30a3\u30fc,\u539f\u5b50\u30b9\u30da\u30af\u30c8\u30ed\u30b9\u30b3\u30d4\u30fc\u306a\u3069\u306e\u5206\u91ce\u3067\u9577\u5e74\u306e\u30ce\u30a6\u30cf\u30a6\u3092\u6301\u3061,\u533b\u85ac\u54c1,\u74b0\u5883\u30c1\u30a7\u30c3\u30af,\u77f3\u6cb9\u5316\u5b66,\u8fb2\u696d,\u6559\u80b2\u306a\u3069\u306e\u5206\u91ce\u3067\u5b8c\u5168\u306a\u7b54\u3048\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059.<\/p>\n<p>PERSEE\u3092\u7279\u5225\u306b\u3059\u308b\u306e\u306f,\u4e16\u754c\u4e2d\u306e\u52a9\u3051\u3067\u6b63\u78ba\u306a\u30c4\u30fc\u30eb\u3092\u4f5c\u308b\u3053\u3068\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3044\u308b\u3053\u3068\u3067\u3059.UV-Vis\u30b9\u30da\u30af\u30c8\u30ed\u30d5\u30a9\u30c8\u30e1\u30fc\u30bf\u30fc\u304b\u3089\u8a73\u7d30\u306a\u30ac\u30b9\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30d5\u307e\u3067\u306e\u65b0\u3057\u3044\u30a2\u30a4\u30c7\u30a2\u306f\u3001\u30b9\u30de\u30fc\u30c8\u306a\u30d3\u30e5\u30fc\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u5f7c\u3089\u306f\u5206\u6790\u3067\u73fe\u5728\u306e\u554f\u984c\u306b\u53d6\u308a\u7d44\u307f\u3001\u4f55\u306e\u305f\u3081\u306e\u8a08\u753b&#8217;\u6b21\u306eS\u3002\u4e16\u754c\u4e2d\u306e\u4eba\u3005\u306f,\u6b63\u3057\u3044\u7d50\u679c,\u5805\u7262\u306a\u69cb\u9020,\u4f7f\u3044\u3084\u3059\u3044\u3053\u3068\u306e\u305f\u3081\u306b,PERSEE\u88fd\u54c1\u306b\u983c\u3063\u3066\u3044\u307e\u3059.<\/p>\n<h2 id=\"summary-remarks-on-defining-and-applying-hrms-resolution\"><strong>HRMS\u6c7a\u8b70\u306e\u5b9a\u7fa9\u3068\u9069\u7528\u306b\u95a2\u3059\u308b\u8981\u7d04<\/strong><\/h2>\n<p>\u89e3\u50cf\u5ea6\u306fHRMS\u6280\u8853\u306e\u6838\u5fc3\u3067\u3059\u3002\u305d\u308c\u306f\u30bf\u30b9\u30af\u3092\u898b\u3064\u3051\u3001\u30ab\u30a6\u30f3\u30c8\u3059\u308b\u305f\u3081\u306b\u6700\u9ad8\u306e\u7cbe\u5ea6\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u89e3\u6790\u5668\u30b9\u30bf\u30a4\u30eb,\u30a4\u30aa\u30f3\u30d1\u30b9\u8a2d\u5b9a,\u4fe1\u53f7\u30ad\u30e3\u30c3\u30c1\u30e3\u30fc\u306a\u3069\u306e\u30c7\u30d0\u30a4\u30b9\u306e\u4e00\u90e8\u306f,\u89e3\u6790\u5ea6\u306e\u30d9\u30fc\u30b9\u3092\u69cb\u7bc9\u3057\u307e\u3059.\u30b9\u30ad\u30e3\u30f3\u30da\u30fc\u30b9\u3084\u30bd\u30fc\u30b9\u6761\u4ef6\u306a\u3069\u306e\u5b9f\u884c\u4e2d\u306e\u8a2d\u5b9a\u306f\u3001\u6700\u5927\u9650\u306e\u5229\u76ca\u3092\u5f97\u308b\u305f\u3081\u306b\u4e00\u81f4\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u6700\u7d42\u7684\u306b\u306f\u3001\u30cf\u30fc\u30c9\u30a6\u30a7\u30a2\u30b1\u30a2\u3068\u30b9\u30de\u30fc\u30c8\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u306e\u30b9\u30c6\u30c3\u30d7\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u304b\u3089\u6700\u9ad8\u306e\u89e3\u50cf\u5ea6\u304c\u5f97\u3089\u308c\u307e\u3059\u3002\u3053\u306e\u7d44\u307f\u5408\u308f\u305b\u306f,\u4f4e\u30ec\u30d9\u30eb\u3067\u78ba\u5b9f\u306a\u7d50\u679c\u3092\u5fc5\u8981\u3068\u3059\u308b\u9818\u57df\u3067\u8cea\u91cf\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u30fc\u304c\u3067\u304d\u308b\u3053\u3068\u3092\u62e1\u5927\u3057\u307e\u3059.<\/p>\n<h2 id=\"faq\"><strong>FAQ\u306b\u3064\u3044\u3066<\/strong><\/h2>\n<p><strong>Q1\uff1a\u8cea\u91cf\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u30fc\u306b\u304a\u3051\u308b\u9ad8\u89e3\u50cf\u5ea6\u5024\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<br \/>\n<\/strong>A1\uff1a\u901a\u5e38\u300110,000\u4ee5\u4e0a\u306e\u89e3\u50cf\u529b\uff08FWHM\u3067m\/\u0394m\uff09\u306f\u9ad8\u89e3\u50cf\u5ea6\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3044\u304f\u3064\u304b\u306e\u5100\u5668\u306f\u5206\u6790\u5668\u306e\u30bf\u30a4\u30d7\u306b\u3088\u3063\u306610\u4e07\u3092\u8d85\u3048\u308b\u3002<\/p>\n<p><strong>Q2: \u9ad8\u89e3\u50cf\u5ea6\u8cea\u91cf\u30b9\u30da\u30af\u30c8\u30ed\u30e1\u30c8\u30ea\u306f\u5b9a\u91cf\u5206\u6790\u306b\u4f7f\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<br \/>\n<\/strong>A2:\u306f\u3044,HRMS\u306f\u8907\u96d1\u306a\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u3067\u3055\u3048\u5b9a\u91cf\u7cbe\u5ea6\u3092\u5411\u4e0a\u3055\u305b\u308b\u512a\u308c\u305f\u9078\u629e\u6027\u3092\u63d0\u4f9b\u3057\u307e\u3059.\u3057\u304b\u3057\u3001\u65b9\u6cd5\u958b\u767a\u306f\u3001\u5668\u5177\u7279\u5b9a\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u8003\u616e\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3002<\/p>\n<p><strong>Q3: \u9ad8\u89e3\u50cf\u5ea6\u306e\u5100\u5668\u3092\u3069\u306e\u304f\u3089\u3044\u983b\u5ea6\u6821\u6b63\u3059\u3079\u304d\u3067\u3059\u304b\u3002<br \/>\n<\/strong>A3: \u6821\u6b63\u5468\u6ce2\u6570\u306f\u4f7f\u7528\u5f37\u5ea6\u306b\u4f9d\u5b58\u3059\u308b\u304c,\u4e00\u822c\u7684\u306b,\u6b63\u78ba\u306a\u8cea\u91cf\u5272\u308a\u5f53\u3066\u3068\u4e00\u81f4\u3057\u305f\u6027\u80fd\u3092\u78ba\u4fdd\u3059\u308b\u305f\u3081\u306b,\u6bce\u65e5\u307e\u305f\u306f\u5404\u5206\u6790\u30d0\u30c3\u30c1\u306e\u524d\u306b\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059.<\/p>","protected":false},"excerpt":{"rendered":"<p>&nbsp; In high resolution mass spectrometry (HRMS), resolution means the device&#8217;s skill in telling apart ions with almost the same mass-to-charge (m\/z) values. This skill matters a lot for spotting compounds correctly, particularly in tricky mixtures. In math terms, resolution shows as R = m\/\u0394m. Here, &#8220;m&#8221; stands for the m\/z at the main peak, and &#8220;\u0394m&#8221; means the peak&#8217;s width at full width at half maximum (FWHM). This way of defining it gives a standard way to check how well different devices perform. People calculate resolution by looking at how two peaks separate based on their average width at the base (tR2 &gt; tR1). A strong resolution allows exact [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4261,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[38,37],"tags":[],"class_list":["post-4265","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-information","category-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/posts\/4265","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/comments?post=4265"}],"version-history":[{"count":4,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/posts\/4265\/revisions"}],"predecessor-version":[{"id":4273,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/posts\/4265\/revisions\/4273"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/media\/4261"}],"wp:attachment":[{"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/media?parent=4265"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/categories?post=4265"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pgeneral.com\/ja\/wp-json\/wp\/v2\/tags?post=4265"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}