{"id":4874,"date":"2026-08-13T13:41:39","date_gmt":"2026-08-13T05:41:39","guid":{"rendered":"https:\/\/www.pgeneral.com\/?p=4874"},"modified":"2026-08-13T13:41:39","modified_gmt":"2026-08-13T05:41:39","slug":"pharmacopoeia-of-the-peoples-republic-of-china-2025-edition-protocol-determination-of-curdione-and-germacrone-in-wenyujin-rhizoma-preparatum","status":"publish","type":"post","link":"https:\/\/www.pgeneral.com\/id\/applications\/pharmacopoeia-of-the-peoples-republic-of-china-2025-edition-protocol-determination-of-curdione-and-germacrone-in-wenyujin-rhizoma-preparatum","title":{"rendered":"Protokol Farmakope Republik Rakyat Tiongkok (Edisi 2025) \u2013 Penentuan Kurdion dan Germakron dalam Sediaan Rimpang Wenyujin"},"content":{"rendered":"<p>Penentuan curdione dan germacrone dalam Wenyujin Rhizoma Preparatum baru saja dimasukkan dalam <em>Farmakope Republik Rakyat Tiongkok (Edisi 2025)<\/em>Sesuai dengan kondisi kromatografi yang tercantum dalam Farmakope Cina Edisi 2025, suatu metode telah ditetapkan untuk analisis kuantitatif curdione dan germacrone dalam Wenyujin Rhizoma Preparatum menggunakan kolom kromatografi C18.<\/p>\n<p>Hasil penelitian menunjukkan bahwa pada uji pengulangan larutan standar referensi: RSD waktu retensi untuk curdione dan germacrone \u2264 0,091%; RSD luas puncak \u2264 0,328%; Faktor pembuntut masing-masing adalah 1,035 dan 1,019; Jumlah pelat teoritis puncak germacrone mencapai 152410, sesuai dengan persyaratan <em>Farmakope Republik Rakyat Tiongkok (Edisi 2025)<\/em>Metode ini dapat dijadikan acuan untuk penentuan curdione dan germacrone dalam Wenyujin Rhizoma Preparatum.<\/p>\n<h2><strong><b>I. Kondisi Instrumen<\/b><\/strong><\/h2>\n<ul>\n<li>Kromatograf Cair Kinerja Tinggi Persee L820<\/li>\n<li>Pompa Gradien Tekanan Tinggi Biner L820-P22<\/li>\n<li>Autosampler L820-A11<\/li>\n<li>Oven Kolom L820-C11<\/li>\n<li>Detektor UV-Vis L820-D10<\/li>\n<li>LCWin V5.0 Stasiun Kerja Kromatografi Standar<\/li>\n<li>Baki Pelarut L820-C304100001<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>The determination of curdione and germacrone in Wenyujin Rhizoma Preparatum is newly included in the Pharmacopoeia of the People\u2019s Republic of China (2025 Edition). In accordance with the chromatographic conditions specified in the 2025 Edition Chinese Pharmacopoeia, a method was established for the quantitative analysis of curdione and germacrone in Wenyujin Rhizoma Preparatum using a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4664,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[36,73],"tags":[],"class_list":["post-4874","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-applications","category-food-and-drugs"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/posts\/4874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/comments?post=4874"}],"version-history":[{"count":1,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/posts\/4874\/revisions"}],"predecessor-version":[{"id":4875,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/posts\/4874\/revisions\/4875"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/media\/4664"}],"wp:attachment":[{"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/media?parent=4874"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/categories?post=4874"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pgeneral.com\/id\/wp-json\/wp\/v2\/tags?post=4874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}