{"id":4874,"date":"2026-08-13T13:41:39","date_gmt":"2026-08-13T05:41:39","guid":{"rendered":"https:\/\/www.pgeneral.com\/?p=4874"},"modified":"2026-08-13T13:41:39","modified_gmt":"2026-08-13T05:41:39","slug":"pharmacopoeia-of-the-peoples-republic-of-china-2025-edition-protocol-determination-of-curdione-and-germacrone-in-wenyujin-rhizoma-preparatum","status":"publish","type":"post","link":"https:\/\/www.pgeneral.com\/de\/applications\/pharmacopoeia-of-the-peoples-republic-of-china-2025-edition-protocol-determination-of-curdione-and-germacrone-in-wenyujin-rhizoma-preparatum","title":{"rendered":"Protokoll des Arzneibuchs der Volksrepublik China (Ausgabe 2025) \u2013 Bestimmung von Curdion und Germacron in Wenyujin-Rhizom-Pr\u00e4paraten"},"content":{"rendered":"<p>Die Bestimmung von Curdion und Germacron in Wenyujin Rhizoma Preparatum ist neu in die Studie aufgenommen worden. <em>Arzneibuch der Volksrepublik China (Ausgabe 2025)<\/em>In \u00dcbereinstimmung mit den in der Ausgabe 2025 des Chinesischen Arzneibuchs festgelegten chromatographischen Bedingungen wurde eine Methode zur quantitativen Analyse von Curdion und Germacron in Wenyujin Rhizoma Preparatum unter Verwendung einer C18-Chromatographies\u00e4ule etabliert.<\/p>\n<p>Die Ergebnisse zeigen, dass in Wiederholbarkeitstests der Referenzstandardl\u00f6sung die relative Standardabweichung (RSD) der Retentionszeit f\u00fcr Curdion und Germacron \u2264 0,091 % betr\u00e4gt; die RSD der Peakfl\u00e4che \u2264 0,328 %; die Tailing-Faktoren 1,035 bzw. 1,019 betragen; die theoretische Bodenzahl des Germacron-Peaks 152410 erreicht und somit die Anforderungen erf\u00fcllt. <em>Arzneibuch der Volksrepublik China (Ausgabe 2025)<\/em>Diese Methode kann als Referenz f\u00fcr die Bestimmung von Curdion und Germacron in Wenyujin Rhizoma Preparatum dienen.<\/p>\n<h2><strong><b>I. Instrumentenbedingungen<\/b><\/strong><\/h2>\n<ul>\n<li>Persee L820 Hochleistungs-Fl\u00fcssigkeitschromatograph<\/li>\n<li>L820-P22 Bin\u00e4re Hochdruck-Gradientenpumpe<\/li>\n<li>L820-A11 Autosampler<\/li>\n<li>L820-C11 S\u00e4ulenofen<\/li>\n<li>L820-D10 UV-Vis-Detektor<\/li>\n<li>LCWin V5.0 Standard-Chromatographie-Workstation<\/li>\n<li>L820-C304100001 L\u00f6sungsmittelwanne<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>The determination of curdione and germacrone in Wenyujin Rhizoma Preparatum is newly included in the Pharmacopoeia of the People\u2019s Republic of China (2025 Edition). In accordance with the chromatographic conditions specified in the 2025 Edition Chinese Pharmacopoeia, a method was established for the quantitative analysis of curdione and germacrone in Wenyujin Rhizoma Preparatum using a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4664,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[36,73],"tags":[],"class_list":["post-4874","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-applications","category-food-and-drugs"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/posts\/4874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/comments?post=4874"}],"version-history":[{"count":1,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/posts\/4874\/revisions"}],"predecessor-version":[{"id":4875,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/posts\/4874\/revisions\/4875"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/media\/4664"}],"wp:attachment":[{"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/media?parent=4874"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/categories?post=4874"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pgeneral.com\/de\/wp-json\/wp\/v2\/tags?post=4874"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}