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Determination of Palladium in Oseltamivir Phosphate by Graphite Furnace Atomic Absorption Spectrometry

  1. Method Overview

After the sample is dissolved in 2% nitric acid, it is injected into the graphite furnace of an atomic absorption spectrophotometer. After electrothermal atomization, it absorbs the resonance line at 247.6nm. Within a certain concentration range, the absorbance is proportional to the palladium content, and quantification is performed by comparison with the standard series.

  1. Scope of Application

Determination of Palladium in Oseltamivir Phosphate

  1. References

Chinese Pharmacopoeia 2020

  1. Instruments and Reagents

4.1 Instruments and Equipment

4.1.1 Detection Instruments

Graphite furnace atomic absorption spectrophotometer (Palladium hollow cathode lamp)

Cooling circulating water system  (Rated water pump flow: 3.5L/min)

4.1.2 Pretreatment Equipment

Ultrapure water system

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